Activity record

PGDB_A030048

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 10-100 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000854
PatentWO2024251301A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007919
Compound IDPGDB_C007919
CompoundNX-6
Source record IDPGDB_C007919
InChIKeyYQNPQDIYXJTZSS-KBVAKVRCSA-N

Assay context

Assay IDPGDB_AS000854
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024251301A1
Compound location

NX-6

NX-6 enlarged structureNX-6 location on patent page 15
Activity table
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