Activity record

PGDB_A031136

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 <= 600 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000845
PatentWO2022219407A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009971
Compound IDPGDB_C009971
Compound57.0
Source record IDPGDB_C009971
InChIKeyAOKLKMXIDQFSLL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000845
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

57.0

57.0 enlarged structure57.0 location on patent page 121
Activity table
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