Activity record

PGDB_A031740

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 0.24971 uM

TargetCRBN
E3 ligaseCRBN
Time2 h
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS002039
PatentCN121378270A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007374
Compound IDPGDB_C007374
Compound实施例1
Source record IDPGDB_C007374
InChIKeyFIRMVPQUUHOJTK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002039
Assay familybinding
Assay systembiochemical
ReadoutIC50
Treatment time2 h
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDCN121378270A
Compound location

实施例1

实施例1 enlarged structure实施例1 location on patent page 14
Activity table
Page 20 · table single