Activity record

PGDB_A032016

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

Dmax = 60-80 %

TargetIKZF1
Cell lineMV-4-11
Time16 h
Assay / ReadoutWestern_blot / Dmax
Assay IDPGDB_AS000264
PatentCN121471230A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001052
Compound IDPGDB_C001052
Compound8;8;实施例8
Source record IDPGDB_C001052
InChIKeyIXEKYQFNTGZTDT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000264
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TechnologyWestern_blot
Treatment time16 h
TargetIKZF1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN121471230A
Compound location

8;8;实施例8

8;8;实施例8 enlarged structure8;8;实施例8 location on patent page 5
Activity table
Page 47 · table single