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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A033128

Assay: % DegradationTarget: IKZF3QC: standardized

Activity overview

degradation < 20 %

TargetIKZF3

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS001967

PatentWO2024245444A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C020071

CompoundGT-07164

Source record IDPGDB_C020071

InChIKeyNHUNFPPGFLTOCX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001967

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF3

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1

Compound location

GT-07164

GT-07164 enlarged structure

GT-07164 location on patent page 94

Activity table

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU