Activity record

PGDB_A033218

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.66 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004164
Compound IDPGDB_C004164
Compound248;248;248
Source record IDPGDB_C021670
InChIKeySOPZIFVPBKCSMS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

248;248;248

248;248;248 enlarged structure248;248;248 location on patent page 45
Activity table
Page 198 · table single