Activity record

PGDB_A033799

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

inhibition = 68.41 %

TargetGSPT1
Cell lineNCI-H69
Time3 d
Assay / Readoutluminescence / % Inhibition
Assay IDPGDB_AS002018
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001865
Compound IDPGDB_C001865
CompoundWX005
Source record IDPGDB_C001865
InChIKeyUSEQRCHYCVHABT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002018
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Technologyluminescence
Treatment time3 d
Detection targetcell_inhibition
TargetGSPT1
E3Not specified
Cell lineNCI-H69

Source evidence

Patent IDWO2023001028A1
Compound location

WX005

WX005 enlarged structureWX005 location on patent page 39
Activity table
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