Activity record

PGDB_A034681

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetGSPT1
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001361
PatentCN120441535A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001531
Compound IDPGDB_C001531
Compound8;实施例8
Source record IDPGDB_C001531
InChIKeyWZCSIIZBDIUSPY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001361
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDCN120441535A
Compound location

8;实施例8

8;实施例8 enlarged structure8;实施例8 location on patent page 58
Activity table
Page 68 · table single