Activity record

PGDB_A035380

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 20-30 %

TargetIKZF3
Cell lineRPMI-8226
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000859
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024217
Compound IDPGDB_C024217
CompoundGT-10057
Source record IDPGDB_C024217
InChIKeyOBOXADZYKCVQHJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000859
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineRPMI-8226
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10057

GT-10057 enlarged structureGT-10057 location on patent page 38
Activity table
Page 157 · table single