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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A036061

Assay: % DegradationQC: ambiguous

Activity overview

degradation = 0-25 %

Cell lineNCI-H929

Concentration20 uM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS001048

PatentEP4065576A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C025205

Compound44;44;44;44

Source record IDPGDB_C025205

InChIKeyADRGMIDOQBZCBE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001048

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration20 uM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF1

E3Not specified

Cell lineNCI-H929

OrganismHomo sapiens

Source evidence

Patent IDEP4065576A1

Compound location

44;44;44;44

44;44;44;44 enlarged structure

44;44;44;44 location on patent page 21

Activity table

Page 136 · table start

Page 137 · table middle

Page 138 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU