Activity record

PGDB_A036358

Assay: viabilityTarget: DDX5QC: ambiguous
Activity overview

IC50 = 1.262 nM

TargetDDX5
Cell lineMDA-MB-453
Time3 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001536
PatentAU2023256446A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006028
Compound IDPGDB_C006028
CompoundDXd
Source record IDPGDB_C006028
InChIKeyPLXLYXLUCNZSAA-QLXKLKPCSA-N

Assay context

Assay IDPGDB_AS001536
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time3 d
Detection target% Cell viability
TargetDDX5
E3Not specified
Cell lineMDA-MB-453

Source evidence

Patent IDAU2023256446A1
Compound location

DXd

DXd enlarged structureDXd location on patent page 101
Activity table
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