PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberAU2023256446A1

AssigneePinotbio

TitleCamptothecin derivatives that bind to ddx5 protein and prodrugs thereof

Family ID88420176

Family members10

Filing year2023

Publication date2024-10-31

JurisdictionAU

Compounds9

Activity records48

Assays6

Activity compounds and values

Activity records

48 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	1.145	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A007351	PGDB_C006029	PGDB_AS001536	View
IC50	-	=	205.4	nM	-	—	DDX5	-	FaDu	PGDB_A012808	PGDB_C006026	PGDB_AS001461	View
IC50	-	=	0.1298	nM	-	—	DDX5	-	FaDu	PGDB_A013385	PGDB_C006033	PGDB_AS001595	View
IC50	-	=	1.528	nM	-	—	DDX5	-	FaDu	PGDB_A017359	PGDB_C006025	PGDB_AS001461	View
IC50	-	=	7.022	nM	-	—	DDX5	-	A549	PGDB_A018274	PGDB_C006027	PGDB_AS001606	View
IC50	-	=	3.369	nM	-	—	DDX5	-	A549	PGDB_A019251	PGDB_C006028	PGDB_AS001606	View
IC50	-	=	73.24	nM	-	—	DDX5	-	FaDu	PGDB_A019714	PGDB_C006028	PGDB_AS001461	View
IC50	-	=	1.331	nM	-	—	DDX5	-	A549	PGDB_A022793	PGDB_C006027	PGDB_AS000151	View
IC50	-	=	14.98	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A023782	PGDB_C006027	PGDB_AS001536	View
IC50	-	=	3.369	nM	-	—	DDX5	-	FaDu	PGDB_A024985	PGDB_C006028	PGDB_AS001461	View
IC50	-	=	2.223	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A028017	PGDB_C006027	PGDB_AS001536	View
IC50	-	=	0.8072	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A029508	PGDB_C006030	PGDB_AS001536	View
IC50	-	=	109	nM	-	—	DDX5	-	FaDu	PGDB_A029927	PGDB_C006027	PGDB_AS001461	View
IC50	-	=	18.48	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A031283	PGDB_C006028	PGDB_AS001536	View
IC50	-	=	109	nM	-	—	DDX5	-	A549	PGDB_A031802	PGDB_C006027	PGDB_AS001606	View
IC50	-	=	1.262	nM	-	—	DDX5	-	MDA-MB-453	PGDB_A036358	PGDB_C006028	PGDB_AS001536	View
IC50	-	=	0.5844	nM	-	—	DDX5	-	A549	PGDB_A043237	PGDB_C006031	PGDB_AS000151	View
IC50	-	=	22.51	nM	-	—	DDX5	-	A549	PGDB_A045122	PGDB_C006025	PGDB_AS001606	View
IC50	-	=	1.555	nM	-	—	DDX5	-	A549	PGDB_A045322	PGDB_C006032	PGDB_AS000151	View
IC50	-	=	0.1298	nM	-	—	DDX5	-	A549	PGDB_A047611	PGDB_C006033	PGDB_AS000151	View

Rows per pagePage 1 of 3 · 48 recordsGo to page