Activity record

PGDB_A036491

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

Dmax = 60.1 %

TargetIKZF1
Cell lineHT-1080
ConcentrationConcentration series: 0.316 nM, 10 uM
Time20 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002293
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007559
Compound IDPGDB_C007559
Compound化合物 15
Source record IDPGDB_C007559
InChIKeyZCHRGDXUBBBTND-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002293
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 0.316 nM, 10 uM
Treatment time20 h
TargetIKZF1
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物 15

化合物 15 enlarged structure化合物 15 location on patent page 112
Activity table
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