Activity record

PGDB_A036671

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

DC50 = 450 nM

TargetIKZF1
Cell lineJurkat
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002379
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010133
Compound IDPGDB_C010133
Compound4
Source record IDPGDB_C010133
InChIKeyIPPKELHFNVYXKG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002379
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetIKZF1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

4

4 enlarged structure4 location on patent page 83
Activity table
Page 88 · table single