Activity record

PGDB_A036954

Assay: viabilityQC: standardized
Activity overview

IC50 = 23.5 nM

Cell lineNCI-H1155
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001656
PatentWO2024125437A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001454
Compound IDPGDB_C001454
Compound实施例 25
Source record IDPGDB_C001454
InChIKeyQMBLTNSCHOGMJC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001656
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection target% Cell viability
E3Not specified
Cell lineNCI-H1155
OrganismHomo sapiens

Source evidence

Patent IDWO2024125437A1
Compound location

实施例 25

实施例 25 enlarged structure实施例 25 location on patent page 34
Activity table
Page 36 · table single