Activity record

PGDB_A037285

Assay: % DegradationTarget: RBM39QC: standardized
Activity overview

IC50 <= 1 uM

TargetRBM39
E3 ligaseDCAF15
Cell lineHCT116
Time<= 1 uM
Assay / ReadoutWestern_blot / IC50
Assay IDPGDB_AS000349
PatentWO2023059899A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010014
Compound IDPGDB_C010014
Compound17;17
Source record IDPGDB_C010014
InChIKeyDKNZIBPDLLYMBP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000349
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
TechnologyWestern_blot
Treatment time<= 1 uM
TargetRBM39
E3DCAF15
Cell lineHCT116
OrganismHomo sapiens

Source evidence

Patent IDWO2023059899A1
Compound location

17;17

17;17 enlarged structure17;17 location on patent page 26
Activity table
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