Activity record

PGDB_A038074

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 90-100 %

TargetIKZF3
Cell lineCCRF-CEM
Concentration500 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS002504
PatentWO2025016359A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019522
Compound IDPGDB_C019522
CompoundGT-07842
Source record IDPGDB_C019522
InChIKeyCFGDAMGLSMBGQF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002504
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineCCRF-CEM
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-07842

GT-07842 enlarged structureGT-07842 location on patent page 42
Activity table
Page 199 · table single