Activity record

PGDB_A038195

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 47 %

TargetNEK7
Cell lineCAL-51
ConcentrationConcentration series: 1 uM, 0.05 nM
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002061
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020433
Compound IDPGDB_C020433
Compound260
Source record IDPGDB_C020433
InChIKeyKZANADYFQMXIQT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002061
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 1 uM, 0.05 nM
Treatment time24 h
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2025024521A1
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