Activity record

PGDB_A038259

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 50-60 %

TargetIKZF3
Cell lineRPMI-8226
Concentration500 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001812
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024253
Compound IDPGDB_C024253
CompoundGT-08711
Source record IDPGDB_C024253
InChIKeyOWABWGWQFQZBOF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001812
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineRPMI-8226
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-08711

GT-08711 enlarged structureGT-08711 location on patent page 46
Activity table
Page 157 · table single