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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A040185

Assay: % DegradationTarget: WEE1QC: standardized

Activity overview

degradation >= 20 %

TargetWEE1

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS000593

PatentWO2025016359A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C019219

CompoundGT-04494

Source record IDPGDB_C019219

InChIKeyWOVGNIQCCOJIES-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000593

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

Detection targetprotein_degradation

TargetWEE1

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1

Compound location

GT-04494

GT-04494 enlarged structure

GT-04494 location on patent page 17

Activity table

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU