Activity record

PGDB_A040461

Assay: % DegradationTarget: SALL4QC: ambiguous
Activity overview

degradation <= 25 %

TargetSALL4
Cell lineNCI-H929
Concentration20 uM
Time24 h
Assay / Readout% Degradation
Assay IDPGDB_AS002409
PatentAU2020392427A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019017
Compound IDPGDB_C019017
Compound6;6
Source record IDPGDB_C019017
InChIKeyYFKKDXHUBCXBEQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002409
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration20 uM
Treatment time24 h
Detection targetprotein_degradation
TargetSALL4
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens

Source evidence

Patent IDAU2020392427A1
Compound location

6;6

6;6 enlarged structure6;6 location on patent page 35
Activity table
Page 114 · table single