Activity record

PGDB_A041008

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 48.9 nM

TargetGSPT1
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002011
PatentIL323841A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008153
Compound IDPGDB_C008153
Compound15
Source record IDPGDB_C008153
InChIKeyKPJVLPULYHOUNE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002011
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDIL323841A
Compound location

15

15 enlarged structure15 location on patent page 54
Activity table
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