Activity record

PGDB_A041053

Assay: % DegradationTarget: VAV1QC: manual_curated
Activity overview

DC50 <= 10 nM

TargetVAV1
Cell lineJurkat
Time24 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS001882
PatentWO2026041143A1
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009248
Compound IDPGDB_C009248
Compound70
Source record IDPGDB_C009248
InChIKeyOWUCJFKZSIGQEG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001882
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time24 h
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat

Source evidence

Patent IDWO2026041143A1
Compound location

70

70 enlarged structure70 location on patent page 50
Activity table
Page 53 · table single