Activity record

PGDB_A042005

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 > 2000 nM

TargetCCNK
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001864
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011978
Compound IDPGDB_C011978
Compound112;112
Source record IDPGDB_C011978
InChIKeyAWCMVVGVQNMVJC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001864
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

112;112

112;112 enlarged structure112;112 location on patent page 75
Activity table
Page 217 · table start
Page 218 · table end