Activity record

PGDB_A042067

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

Dmax = 17.3 %

TargetGSPT1
Cell lineHEK293
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001278
PatentWO2025224262A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011769
Compound IDPGDB_C011769
Compound146
Source record IDPGDB_C011769
InChIKeyKNVWWGVIZSEPEL-QTXYGZLBSA-N

Assay context

Assay IDPGDB_AS001278
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025224262A1
Compound location

146

146 enlarged structure146 location on patent page 22
Activity table
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