Activity record

PGDB_A042088

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

degradation = 89.5 %

TargetIKZF2
Concentration1 uM
Assay / Readout% Degradation
Assay IDPGDB_AS000892
PatentWO2024059107A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002824
Compound IDPGDB_C002824
Compound60;60;60
Source record IDPGDB_C002824
InChIKeyXKHJZGRFJRADNW-ONNFQVAWSA-N

Assay context

Assay IDPGDB_AS000892
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration1 uM
Detection targetprotein_degradation
TargetIKZF2
E3Not specified

Source evidence

Patent IDWO2024059107A1
Compound location

60;60;60

60;60;60 enlarged structure60;60;60 location on patent page 9
Activity table
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