Activity record

PGDB_A042549

Assay: viabilityTarget: ESR1QC: standardized
Activity overview

IC50 = 4.3 nM

TargetESR1
Cell lineMCF-7
Time5 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001905
PatentRU2847441C1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008965
Compound IDPGDB_C008965
Compound实施例2
Source record IDPGDB_C008965
InChIKeyKJAAPZIFCQQQKX-MUUNZHRXSA-N

Assay context

Assay IDPGDB_AS001905
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time5 d
Detection target% Cell viability
TargetESR1
E3Not specified
Cell lineMCF-7

Source evidence

Patent IDRU2847441C1
Compound location

实施例2

实施例2 enlarged structure实施例2 location on patent page 62
Activity table
Page 66 · table start