Activity record

PGDB_A042941

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.48 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004163
Compound IDPGDB_C004163
Compound235;235;235
Source record IDPGDB_C021634
InChIKeyXAZBAFYAKKTPIP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

235;235;235

235;235;235 enlarged structure235;235;235 location on patent page 44
Activity table
Page 198 · table single