Activity record

PGDB_A043966

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 92 %

TargetNEK7
Cell lineCAL-51
ConcentrationConcentration series: 1 uM, 0.05 nM
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002061
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020304
Compound IDPGDB_C020304
Compound53
Source record IDPGDB_C020226
InChIKeyBITYGUQDRHUTJX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002061
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 1 uM, 0.05 nM
Treatment time24 h
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2025024521A1
Activity table
Page 414 · table start
Page 415 · table middle
Page 416 · table end