Activity record

PGDB_A044458

Assay: % DegradationTarget: KDM4BQC: ambiguous
Activity overview

degradation = 73 %

TargetKDM4B
Cell lineBE2C
Concentration0.1 uM
Time24 h
Assay / Readout% Degradation
Assay IDPGDB_AS001565
PatentWO2025199151A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011583
Compound IDPGDB_C011583
Compound14
Source record IDPGDB_C011583
InChIKeyHMBOHFGRYWBSDZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001565
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration0.1 uM
Treatment time24 h
TargetKDM4B
E3Not specified
Cell lineBE2C
OrganismHomo sapiens

Source evidence

Patent IDWO2025199151A1
Compound location

14

14 enlarged structure14 location on patent page 119
Activity table
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