Activity record

PGDB_A044797

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

degradation < 25 %

TargetGSPT1
Cell lineMV-4-11
Time16 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS000065
PatentCN121471230A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001058
Compound IDPGDB_C001058
Compound14;14;实施例14
Source record IDPGDB_C001058
InChIKeyBGPLHUYFYCGDHC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000065
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Treatment time16 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN121471230A
Compound location

14;14;实施例14

14;14;实施例14 enlarged structure14;14;实施例14 location on patent page 5
Activity table
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