Activity record

PGDB_A045322

Assay: viabilityTarget: DDX5QC: ambiguous
Activity overview

IC50 = 1.555 nM

TargetDDX5
Cell lineA549
Time3 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000151
PatentAU2023256446A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006032
Compound IDPGDB_C006032
CompoundSN-38
Source record IDPGDB_C006032
InChIKeyFJHBVJOVLFPMQE-QFIPXVFZSA-N

Assay context

Assay IDPGDB_AS000151
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time3 d
Detection target% Cell viability
TargetDDX5
E3Not specified
Cell lineA549

Source evidence

Patent IDAU2023256446A1
Compound location

SN-38

SN-38 enlarged structureSN-38 location on patent page 101
Activity table
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