Activity record

PGDB_A045356

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 > 1900 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000845
PatentWO2022219407A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009924
Compound IDPGDB_C009924
Compound2
Source record IDPGDB_C009924
InChIKeyQZELYYTUBCOLMU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000845
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

2

2 enlarged structure2 location on patent page 118
Activity table
Page 181 · table start
Page 182 · table end