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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A045431

Assay: % DegradationTarget: GSPT1QC: ambiguous

Activity overview

DC50 > 10000 nM

TargetGSPT1

Cell line293T.114

TimeDC50 > 10000 nM

Assay / Readoutluminescence / DC50

Assay IDPGDB_AS002445

PatentAU2021361043A9

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C016642

Compound106;106;106

Source record IDPGDB_C016642

InChIKeyVKGFVJJGIGCFKX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002445

Assay family% Degradation

Assay systemcell_based

ReadoutDC50

Technologyluminescence

Treatment timeDC50 > 10000 nM

TargetGSPT1

E3Not specified

Cell line293T.114

OrganismHomo sapiens

Source evidence

Patent IDAU2021361043A9

Compound location

106;106;106

106;106;106 enlarged structure

106;106;106 location on patent page 249

Activity table

Page 287 · table start

Page 288 · table middle

Page 289 · table middle

Page 290 · table middle

Page 291 · table middle

Page 292 · table middle

Page 293 · table middle

Page 294 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU