Activity record

PGDB_A045888

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 24.34 nM

TargetGSPT1
Cell lineNCI-H1299
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002069
PatentCN120365257A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000739
Compound IDPGDB_C000739
Compound实施例 05;实施例05
Source record IDPGDB_C000739
InChIKeyVJWHZBCDZCYYDV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002069
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1299

Source evidence

Patent IDCN120365257A
Compound location

实施例 05;实施例05

实施例 05;实施例05 enlarged structure实施例 05;实施例05 location on patent page 5
Activity table
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