Activity record

PGDB_A045965

Assay: viabilityTarget: BRAFQC: standardized
Activity overview

GI50 = 794 nM

TargetBRAF
Cell lineA375-NRASQ61K
Time96 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS001149
PatentAU2022290851A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005653
Compound IDPGDB_C005653
Compound157NMe
Source record IDPGDB_C005653
InChIKeyDJRCVRCCOYKCIV-MUUNZHRXSA-N

Assay context

Assay IDPGDB_AS001149
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time96 h
TargetBRAF
E3Not specified
Cell lineA375-NRASQ61K

Source evidence

Patent IDAU2022290851A1
Compound location

157NMe

157NMe enlarged structure157NMe location on patent page 801
Activity table
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