Activity record

PGDB_A045985

Assay: % DegradationTarget: IKZF3QC: standardized
Activity overview

DC50 > 30 uM

TargetIKZF3
Cell lineHEK293T
Time24 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS001025
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000381
Compound IDPGDB_C000381
Compound10;10;10
Source record IDPGDB_C000381
InChIKeyDQYZQRGRHXEYPT-SDHOMARFSA-N

Assay context

Assay IDPGDB_AS001025
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDUS20230265071A1
Compound location

10;10;10

10;10;10 enlarged structure10;10;10 location on patent page 31
Activity table
Page 166 · table single