Activity record

PGDB_A047175

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

DC50 = 0.014 nM

TargetIKZF1
Cell lineHT-1080
Time20 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002064
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007564
Compound IDPGDB_C007564
Compound化合物 20
Source record IDPGDB_C007564
InChIKeyVGYLUWYHUSGMPW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002064
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time20 h
TargetIKZF1
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物 20

化合物 20 enlarged structure化合物 20 location on patent page 114
Activity table
Page 122 · table single