Activity record

PGDB_A047460

Assay: viabilityTarget: IKZF3QC: ambiguous
Activity overview

inhibition = 5-10 %

TargetIKZF3
Cell lineKasumi-1
Concentration10 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001962
PatentWO2025016359A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019524
Compound IDPGDB_C019524
CompoundGT-08003
Source record IDPGDB_C019524
InChIKeySMPXJTALQPIZLO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001962
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineKasumi-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-08003

GT-08003 enlarged structureGT-08003 location on patent page 56
Activity table
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