Activity record

PGDB_A047897

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.006379 nM

TargetKRAS
Cell lineAGS
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000075
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011605
Compound IDPGDB_C011605
CompoundExample 18
Source record IDPGDB_C011605
InChIKeyQDFUYTVFSGSPQA-FQDQCCRJSA-N

Assay context

Assay IDPGDB_AS000075
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineAGS
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Example 18

Example 18 enlarged structureExample 18 location on patent page 58
Activity table
Page 226 · table single