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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A047924

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

degradation = 50-79 %

TargetGSPT1

Cell lineHep3B

Concentration10 uM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS001312

PatentCN116457344A

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C000052

Compound20;20;20;20;20;20

Source record IDPGDB_C000052

InChIKeyQQYCWUSAEZSMCN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001312

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration10 uM

Treatment time24 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell lineHep3B

Source evidence

Patent IDCN116457344A

Compound location

20;20;20;20;20;20

20;20;20;20;20;20 enlarged structure

20;20;20;20;20;20 location on patent page 11

Activity table

Page 91 · table start

Page 92 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU