Activity record

PGDB_A048781

Assay: % DegradationTarget: BLOC1S6QC: ambiguous
Activity overview

EC50 = 0.73 uM

TargetBLOC1S6
Cell lineHEK293T
Time24 h
Assay / ReadoutEC50 / % Degradation
Assay IDPGDB_AS002145
PatentJP2024545831A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008301
Compound IDPGDB_C008301
CompoundC5
Source record IDPGDB_C008301
InChIKeyTXPBERWYEQCNQG-MRMRVTFPSA-N

Assay context

Assay IDPGDB_AS002145
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Treatment time24 h
TargetBLOC1S6
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDJP2024545831A
Compound location

C5

C5 enlarged structureC5 location on patent page 26
Activity table
Page 27 · table single