Activity record

PGDB_A049276

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 0.0001-0.01 uM

TargetGSPT1
E3 ligaseCRBN
Cell lineKG-1
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001194
PatentCN118234721A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019828
Compound IDPGDB_C019828
Compound化合物 46
Source record IDPGDB_C001240
InChIKeyNYERMAZWASNMSE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001194
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
TargetGSPT1
E3CRBN
Cell lineKG-1

Source evidence

Patent IDCN118234721A
Compound location

化合物 46

化合物 46 enlarged structure化合物 46 location on patent page 41
Activity table
Page 63 · table start
Page 64 · table end