Activity record

PGDB_A049526

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 10-50 uM

TargetGSPT1
E3 ligaseCRBN
Cell lineKG-1
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001194
PatentCN118234721A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019836
Compound IDPGDB_C019836
Compound比较物质
Source record IDPGDB_C001248
InChIKeyIKUDMBCBGPFJRR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001194
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
TargetGSPT1
E3CRBN
Cell lineKG-1

Source evidence

Patent IDCN118234721A
Compound location

比较物质

比较物质 enlarged structure比较物质 location on patent page 64
Activity table
Page 63 · table start
Page 64 · table end