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SIMM · NJU
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SIMM · NJU
Activity record
PGDB_A050455
Assay: ternary_complex
Target: ALK
QC: standardized_posthoc
Activity overview
EC50 = 10-100 nM
Target
ALK
E3 ligase
CRBN
Time
2 h
Assay / Readout
Fold change / ternary_complex
Assay ID
PGDB_AS002152
Patent
WO2026015344A1
QC status
standardized_posthoc
Evidence details
Compound, assay context, and source
Compound
Compound ID
PGDB_C012359
Compound
88
Source record ID
PGDB_C012359
InChIKey
GZRGQERVYXIKMK-UHFFFAOYSA-N
Assay context
Assay ID
PGDB_AS002152
Assay family
ternary_complex
Assay system
biochemical
Readout
Fold change
Treatment time
2 h
Target
CRBN | DDB1
E3
CRBN | DDB1
Source evidence
Patent ID
WO2026015344A1
Compound location
88
Activity table