Activity record

PGDB_A054039

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetGSPT1
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001361
PatentCN120441535A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001535
Compound IDPGDB_C001535
Compound12;实施例12
Source record IDPGDB_C001535
InChIKeyXWVQZSSVYCTKPQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001361
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDCN120441535A
Compound location

12;实施例12

12;实施例12 enlarged structure12;实施例12 location on patent page 65
Activity table
Page 68 · table single