Activity record

PGDB_A055623

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

degradation = 84.5 %

TargetIKZF2
Cell lineHEK293T
Concentration1 uM
Time24 h
Assay / Readoutfluorescence / % Degradation
Assay IDPGDB_AS000641
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000386
Compound IDPGDB_C000386
Compound19;19
Source record IDPGDB_C000386
InChIKeyZYORMCAFNGNXPP-QBGWGINNSA-N

Assay context

Assay IDPGDB_AS000641
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyfluorescence
Concentration1 uM
Treatment time24 h
TargetIKZF2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDUS20230265071A1
Compound location

19;19

19;19 enlarged structure19;19 location on patent page 33
Activity table
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