Activity record

PGDB_A056155

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.09446 nM

TargetKRAS
Cell lineAsPC-1
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS001593
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011604
Compound IDPGDB_C011604
CompoundExample 17;Example 17
Source record IDPGDB_C011604
InChIKeyYNNLIRCRYKYBPT-XXGQOMGMSA-N

Assay context

Assay IDPGDB_AS001593
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineAsPC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Example 17;Example 17

Example 17;Example 17 enlarged structureExample 17;Example 17 location on patent page 58
Activity table
Page 226 · table single