Activity record

PGDB_A057179

Assay: viabilityTarget: BRAFQC: standardized
Activity overview

GI50 = 22.5 nM

TargetBRAF
Cell lineA375
Time72 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS000079
PatentAU2022290851A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005653
Compound IDPGDB_C005653
Compound157NMe
Source record IDPGDB_C005653
InChIKeyDJRCVRCCOYKCIV-MUUNZHRXSA-N

Assay context

Assay IDPGDB_AS000079
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time72 h
TargetBRAF
E3Not specified
Cell lineA375

Source evidence

Patent IDAU2022290851A1
Compound location

157NMe

157NMe enlarged structure157NMe location on patent page 801
Activity table
Page 808 · table single