Activity record

PGDB_A058071

Assay: % DegradationTarget: SALL4QC: standardized
Activity overview

Dmax = 76.5 %

TargetSALL4
Cell lineHT-1080
ConcentrationConcentration context: HiBiT SALL4:_D max (%)
Time20 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001879
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007547
Compound IDPGDB_C007547
Compound化合物 5
Source record IDPGDB_C007547
InChIKeyKLOSPRVZJHFKOX-SYQKMTEESA-N

Assay context

Assay IDPGDB_AS001879
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration context: HiBiT SALL4:_D max (%)
Treatment time20 h
Detection targetprotein_degradation
TargetSALL4
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物 5

化合物 5 enlarged structure化合物 5 location on patent page 106
Activity table
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